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FRESH DR. HONG CLINIC
Skin quality is not determined by moisture alone.
The supporting structural framework of the skin must be restored.
RE2O ECM
RE2O ECM helps reinforce the structural environment that supports the skin.
It gently improves areas of volume loss while refining skin firmness and texture.
Through Elravie RE2O, this program is designed to enhance both skin quality and three-dimensional facial balance.
What Is RE2O ECM Program at Fresh?
RE2O ECM precisely adds subtle volume where needed, enhancing natural facial dimension while supporting smooth contours and healthy skin radiance.
When skin condition improvement and structural volume support are addressed together, the result is a more refined, balanced, and youthful appearance.

The formula contains components such as: Collagen, Elastin,ECM proteins and Glycosaminoglycans (GAG). These ingredients may help support skin hydration, texture refinement, and elasticity maintenance.

This program connects skin quality improvement with facial contour design, creating a harmonious transformation that focuses not only on the surface, but also on the underlying skin structure.

It is a premium treatment designed to enhance both skin and structure simultaneously.
Basic Treatment Information
수술시간
Procedure time
20–30 minutes
마취방법
Anesthesia
Topical cream anesthesia
실밥제거
Hospital stay
None (same-day discharge)
입원치료
Suture removal
Not required
모델
Key Features of RE2O ECM
CHECK POINT
Improvement of the ECM Skin Environment
By optimizing the balance of the skin’s extracellular matrix (ECM), the treatment supports stable improvement in texture, hydration, and elasticity.
CHECK POINT
Three-Dimensional Contour Design
Subtle density is added to areas that require support, helping soften volume loss and create natural facial dimension, resulting in a soft yet well-defined youthful appearance.
CHECK POINT
Simultaneous Approach to Skin Quality and Contour
When skin condition improvement and structural support are addressed together, the result is a clearer, more refined, and balanced facial impression.
CHECK POINT
Fresh Dr. Hong Facial Analysis System
Based on facial proportions and structural analysis, areas with weakened support are precisely reinforced to achieve natural-looking balance without obvious signs of treatment.
Recommended Candidates for RE2O ECM
01
Have a long facial shape with noticeable volume loss
02
Desire a younger-looking facial proportion with a shorter midface appearance
03
Prefer non-surgical options instead of fat grafting
04
Feel uncomfortable with traditional fillers due to the foreign-body sensation
05
Are concerned about reduced skin elasticity and fine wrinkles
06
Did not achieve the expected improvement from previous skin booster treatments
RE2O ECM Treatment Areas
모델
CASE
RE2O ECM can be applied to the following areas
Eye area / Under-eye area / yelids / Aegyo-sal (under-eye volume line) / Corners of the mouth /
Nose bridge / Lips / Horizontal and vertical neck lines / Back of the hands
Next-Generation RE2O ECM with Real Human Skin Technology
Elravie Re2O
The FIRST
A first in the aesthetic market
Unlike animal-derived or synthetic ingredients, it utilizes human-derived ECM components and is the world’s first acellular human dermal matrix (hADM) booster designed for aesthetic treatments.
Safety & Biocompatibility
Verified safety
Through the AlloClean Technology process, residual DNA is minimized to enhance safety. The raw materials are based on components approved by American Association of Tissue Banks, Ministry of Food and Drug Safety, and U.S. Food and Drug Administration, supporting a high level of biocompatibility.
All in One Care
Comprehensive skin concerns management
Rather than focusing on a single effect, the treatment considers multiple aspects of skin improvement simultaneously, including: brightening, wrinkle improvement, skin elasticity, pore appearance and skin texture refinement
Fresh RE2O ECM (Extracellular Matrix)
ECM (Extracellular Matrix) is a complex biological structure composed of macromolecules that fill the spaces between cells, forming an essential structural framework of the skin.
It helps: protect cells, support the skin’s structural integrity and maintain elasticity and tissue stability
Key components such as collagen, elastin, fibronectin, and laminin play important roles in cell adhesion and the wound-healing process.
ECM also functions as a reservoir for growth factors, supporting the skin’s regeneration and recovery processes.
모델
Immediate Volume, Longer-Lasting Results
RE2O ECM helps strengthen the skin’s structural framework by promoting the increase of collagen and elastin, improving the skin’s ability to maintain volume.
At the same time, the moisture-binding properties of hyaluronic acid help the skin stay hydrated for longer.
The result is a visible difference in volume and skin quality that continues to last over time.
모델
Even after 6 month collagen and elastin density remains maintained.
RE20 ECM: Integrated Regeneration Designed from Surface to Structure
A comprehensive regenerative approach that addresses both visible skin changes and the underlying structural environment,
helping the skin maintain greater long-term stability.
Hand Injection
(superficial dermal layer)
손주사 시술 이미지
Cannula Technique
(deep dermis and subcutaneous fat layer)
캐눌라 시술 이미지
Category
RE2O Skin
RE2O ECM Volume
Injection Method
Hand injection (manual syringe)
Micro-cannula injection
Injection Target Layer
Epidermis / superficial dermis (shallow layer)
Lower dermis / subcutaneous layer (deeper layer)
Pain Level
Mild stinging sensation
Relatively low and comfortable
Main Effects
Improves skin texture and enlarged pores
Volume enhancement and contour line improvement
Down
time
Temporary redness
Minimal swelling and recovery burden
Q. How often should RE2O ECM treatments be performed?
+
In general, 2–3 treatment sessions at intervals of about one month are recommended. The exact schedule may vary depending on an individual’s skin condition and treatment goals. Completing the recommended number of sessions can help extend the duration of results and maximize skin regeneration effects.
Q. When will I start to see results from RE2O ECM?
+
Immediately after the procedure, patients may notice smoother skin texture and subtle volume improvement. Afterward, the ECM components stimulate collagen production within the skin, leading to gradual improvements in elasticity. Noticeable collagen regeneration typically begins around 2–4 weeks after treatment. Although results may vary depending on the individual, it is generally reported that after three or more sessions, results can last from 6 months to over one year.
Q. . Is the RE2O ECM treatment painful?
+
During the procedure, some patients may experience temporary stinging or mild tightness, though this varies from person to person. With adequate application of topical anesthetic cream and the experienced technique of Dr. Hong at Fresh, discomfort during the procedure can generally be minimized.

Stem Cells&Treatments 의 RE2O ECM 페이지 입니다.

신사동 RE2O ECM , 강남 RE2O ECM , 압구정 RE2O ECM

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Fresh Dr. Hong
Excellence is not a skill,
it’s an attitude
Fresh Dr.Hong Clinic incorporates state-of-the-art technologies and advanced medical equipment, adhering to safety guidelines and principles. It goes beyond conventional face and body contouring by revolutionizing the industry with its exceptional excellence.
FRESH DR. HONG CLINIC FRESH DR. HONG CLINIC
Enhancing natural beauty
making you smile. Enhancing natural beauty
making you smile.
Fresh Dr.Hong Clinic keeps fingers on the pulse of industry trends and continuously investigating development of our skill to to provide satisfaction and happiness to those who trust and visit our clinic.
Contact
Contact Number
8210-2140-90818210-2140-9081
Open Hours
Weekdays  AM 10:00 - PM 07:00
Saturday  AM 10:00 - PM 05:00
Sunday & Holidays Closed
location
Direction
Address
3rd F, Shinsahill B/D., 563-17, Sinsa-Dong, Gangnam_Gu, Seoul, Korea
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